Situated a 6-minute walk from Maschio Angioino, B&B Palazzo Depretis features rooms with air conditioning in Naples. Popular points of interest nearby include Molo Beverello and San Carlo Theatre. The accommodation offers a concierge service and a tour desk for guests.

At the bed and breakfast, each room is fitted with a desk, a flat-screen TV and a private bathroom. B&B Palazzo Depretis provides some rooms with city views, and all rooms are equipped with a balcony. The rooms feature a wardrobe.

A sweet, Italian-style breakfast is served daily on site.

Palazzo Reale Napoli is 800 m from B&B Palazzo Depretis, while San Gregorio Armeno is a 10-minute walk from the property. Naples International Airport is 5 km away.